Preheat oven to 400ºF. Spray 16 wells of two 12-count muffin pans with non-stick spray or line the wells with cupcake liners. Set aside.
In a large bowl, toss together 2 and ½ cups of the flour, baking powder, baking soda, and salt. Set aside.
In a medium size bowl, whisk together the brown sugar, granulated sugar, and butter until smooth. Add the eggs, orange juice/milk mixture, orange zest, and vanilla extract and whisk again until everything is combined.
Pour the wet ingredients into the dry ingredients and stir gently with a spatula until just combined. Set aside.
In a medium size bowl or a colander over the sink, toss the blueberries in the remaining 2 Tablespoons of flour. Carefully fold the blueberries into the muffin batter, being aware the purple color will spread a bit.
Spoon batter equally into prepared muffin pans. Place additional blueberries in the tops of the muffins if desired. Sprinkle each muffin with coarse sugar, if using. Bake muffins for 5 minutes, then reduce heat to 350ºF and bake for an additional 15-16 minutes until tops start to brown and a toothpick inserted in the center comes out mostly clean. Remove from oven and allow to cool completely on a wire rack. Muffins will stay fresh in an airtight container at room temperature up to 3 days or in the refrigerator up to one week. Muffins freeze well, up to 2 months. Thaw in microwave for 45-60 seconds before eating.
Notes
It is always a good rule of thumb to use room temperature eggs when using room temperature butter. To bring eggs to room temperature quickly, place in a bowl of warm water for 10 minutes.
This means: add 1 Tablespoon of orange juice to a glass measuring cup. Add milk to the cup with the orange juice until the level is at 3/4 cup. This is similar to making buttermilk.
You may also use fresh blueberries or a combination of fresh and frozen.
Nutrition Disclosure
All nutritional values are approximate and provided to the reader as a courtesy. Changing ingredients and/or quantities will alter the estimated nutritional calculations.